Overweight and obese patients given the Mid-dose of Qnexa, containing 7.5 mg of phentermine plus 46 mg of Topamax (topiramate), lost an average weight loss of roughly 19 pounds versus 5 pounds with placebo after one year, or 8.4 percent of body weight versus 1.8 percent with placebo according to a press release from press release from Vivus, Inc, the company developing the drug.
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