Maybe. A 1990 study found that after three weeks of drinking three-and-a-half cans of high-fructose corn syrup-sweetened soda daily women gained an average of +2.1 pounds while men gained +1.1 pounds.1 The reason for the weight gain was simple ? they consumed 13 percent more calories per day. Men consumed 374 calories and women 247 calories more each day. When the same subjects were given sodas sweetened with NutraSweet? (aspartame) for three weeks calorie intake was 7 percent lower than normal. Women gained an average of +0.6 pounds, which was not statistically significant, while men lost -1 pound.
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