There were fewer heart attacks, fewer heart bypasses performed, fewer cardiovascular deaths, and fewer total deaths during a 14 month period in statin users given extended-release niacin compared to those given Zetia (ezetimibe) according to a study published in the New England Journal of Medicine. The final dose of extended-release niacin was:
In rare cases, niacin can cause liver problems. This is more common with extended-release niacin than regular niacin. This is because extended-release niacin (or time-release niacin) is roughly the equivalent of double the dose of regular niacin as noted by Dr. William Parsons in the 1993 book Coronary Heart Disease: The Dietary Sense and Nonsense. An evaluation by scientists.
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