Giving the dopamine agonist cabergoline (Dostinex, Cabaser) or bromocriptine (Parlodel) to heavy men with prolactinoma—a noncancerous pituitary tumor that produces the hormone prolactin and causes prolactin levels to be be greatly elevated—appears to cause weight loss. Weight loss seems to occur in heavy men only, whereas lean men gained weight. One woman gained 33 lbs, however, in the other 16 women, there did not appear to be much of a weight change after 6 months. This is based on a very small sample size—only 3 heavy men and 2 lean men—so these results should be viewed as very preliminary. By approximating body weight from a chart in the paper, here are the weight changes in the 5 men.
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