People given 7.5 mg of phentermine plus 46 mg of Topamax (topiramate) lost an average of 17.8 pounds in one year versus a weight loss of 3.1 pounds in those given a placebo according to a new study from Duke University in Durham, North Carolina, USA. The weight loss represented 7.8 percent of body weight for the drug group versus 1.2 percent for the placebo group.
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