Obese men and women given 15 mg of controlled-release phentermine plus 92 mg of controlled-release topiramate (Topamax)—the trade name of this drug combination is Qnexa— lost an average of 10.9% of body weight after one-year compared to an average weight loss of 1.6% for those given a placebo according to a study from the researchers at the University of Alabama at Birmingham.
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