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Obesity is a chronic inflammatory state; benefits of weight loss due to reduction of inflammation
Thursday, June 10, 2004 2:05 pm Email this article
"The success of weight loss surgery in treating the complications associated with obesity is most probably related to the reduction of inflammatory mediators," concludes a paper from researchers at the Obesity and Nutrition Research Center, Department of Surgery, from The University of Pittsburgh Medical Center, in Pittsburgh, Penn.
“OBESITY [IS] A CHRONIC INFLAMMATORY STATE”
“[T]here appears to be a strong association between obesity and inflammation, thereby rendering obesity a chronic inflammatory state,” the authors of the paper state.
INFLAMMATION AFFECTS BLOOD PRESSURE, CHOLESTEROL, CANCER, INFECTIONS AND OTHERS
These inflammatory mediators have a detrimental effect on
- dyslipidemia (unhealthy cholesterol levels or triglyceride levels)
- thromboembolic phenomena (the blocking of a blood vessel by a blood clot)
- infections, and
Cottam D, Mattar S, Barinas-Mitchell E, Eid G, Kuller L, Kelley D, Schauer P. The chronic inflammatory hypothesis for the morbidity associated with morbid obesity: implications and effects of weight loss. Obes Surg. 2004 May, 14(5):589-600.
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