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  • Qsymia (phentermine / topiramate) can increase heart rate; risk of heart attack and stroke not known

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    Wednesday, July 18, 2012 2:50 pm Email this article

    Qsymia (phentermine plus topiramate) "can increase heart rate; this drug’s effect on heart rate in patients at high risk for heart attack or stroke" is not known notes the FDA press release.

    “Therefore, the use of Qsymia in patients with recent (within the last six months) or unstable heart disease or stroke is not recommended.

    “Regular monitoring of heart rate is recommended for all patients taking Qsymia, especially when starting Qsymia or increasing the dose.”

    “Qsymia will only be dispensed through specially certified pharmacies. 

    Drug Company to assess long-term risk of cardiac problems

    Vivus to conduct long-term evaluation of the risk of heart attack and stroke

    “Vivus Inc. will be required to conduct 10 postmarketing requirements, including a long-term cardiovascular outcomes trial to assess the effect of Qsymia on the risk for major adverse cardiac events such as heart attack and stroke.”


    FDA. FDA approves weight-management drug Qsymia. July 17, 2012.

    More Info

    More info about Qsymia here

    Drug companies website:

    Other Articles

    Other articles about Qsymia (formerly Qnexa)

    Articles on the same subject can be found here:


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