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Obese mice will make fat out of their food even when half-starved, Gary Taubes
Wednesday, January 18, 2012 11:59 am Email this article
When obese mice were put on a strict diet to get their body weight below that of lean mice, they "still contain more fat than the normal ones, while their muscles have melted away", Gary Taubes notes in his excellent book Why We Get Fat and What To Do About It.
In the 1950's, Jean Mayer, a Harvard researcher, noted that these obese mice 'will make fat out of their food under the most unlikely circumstances, even when half starved."
The point of this is, as Taubes states repeatedly, that all of these animals become obese, not because of faulty appetite regulation, but because of a change in the regulation of fat tissue which causes their fat cells to suck up more calories which leaves other tissue (muscles and organs) starved for energy which causes these animals to eat more and exercise less. Putting obese mice on a normal diet causes their muscles to waste away
They make fat out of food even when half-starved
“The same thing holds true for aninlals that are bred to be obese, for which obesity is in their genes,” Taubes writes.
“In the 1950s, Jean Mayer studied one such strain of obese mice in his Harvard laboratory.
“As he reported it, he could get their weight below that of lean mice if he starved them sufficiently, but they’d ‘still contain more fat than the normal ones, while their muscles have melted away.’”
“Once again, eating too much wasn’t the problem; these mice, as Mayer wrote, ‘will make fat out of their food under the most unlikely circumstances, even when half starved.”This is a MUST-READ Book
This is MUST-READ book for anyone interested in body weight
This is MUST-READ book for anyone interested in body weight… or anyone who believes that saturated fat is bad for you… or anyone who believes that carbohydrates are good for you… or anyone who believes that obesity is caused by a lack of will power… or anyone who believes that obesity is caused by eating too much and exercising too little (yes, of course this is true, but this does not answer the question as to why people eat too much and exercise too little, which Taubes answers in this book).
I highly recommend this book.
Gary Taubes is an excellent science journalist.
His previous books include “Good Calories, Bad Calories”, a longer book which is also about low-carb diets, but is a much longer book.Other Articles from This Book, Why We Get Fat
Articles from Gary Taubes current book, Why We Get Fat
Other Articles from Good Calories, Bad Calories
Articles about Gary Taubes previous book, Good Calories, Bad Calories
Contact info for Gary Taubes
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