fatnews.com Home page  >  Article | Previous article | Next article

SEARCH

QUICKLINKS AND VIEW OPITONS

  • Categories of Articles
  • Summary View
  • Headline View
  • Archive of Quotes
  • Contact Us
  • Follow @fatnews

    Topamax (topiramate) caused average weight gain of 5.3 lbs in six months in migraine suffers


    Posted by .(JavaScript must be enabled to view this email address)
    Monday, April 04, 2011 3:26 pm Email this article
    Topamax (topiramate) caused average weight loss of 5.3 lbs in six months in patients given the drug for as a preventative against migraine headaches according to a recent study. Subjects

    Subjects: 331 adults, mostly women, with 3-12 migraines per month

    The study involved 331 subjects (172 topiramate, 159 amitriptyline) who had 3 to 12 migraines per month.

    Eighty-five percent 85% female, and 85% were white.

    The average age was 39-years-old.

    Their average starting weight was 169 lbs.

     

    Dose

    Dose: 25 mg per day increased to 100 mg per day

    The dose used was 25 mg per day of either topiramate (Topamax) or amitriptyline (Elavil), “subsequently titrated to a maximum of 100 mg/d (or the maximum tolerated dose).”

    REFERENCE

    Dodick D, Freitag F, Banks J, Saper J, Xiang J, Rupnow M, Biondi D, Greenberg S, Hulihan J. Topiramate versus amitriptyline in migraine prevention: A 26-week, multicenter, randomized, double-blind, double-dummy, parallel-group noninferiority trial in adult migraineurs. Clin Ther. 2009 Mar, 31(3):542-59.

    AUTHOR’S CONTACT INFORMATION

    David W. Dodick, MD
    Department of Neurology
    Mayo Clinic Hospital
    5777 E. Mayo Boulevard
    Phoenix, AZ 85054 USA
    .(JavaScript must be enabled to view this email address)

    Articles on the same subject can be found here:


    COMMENTS

    Please feel free to share your comments about this article.


    Name:

    Email:

    Comments:

    Please enter the word you see in the image below:


    Remember my personal information

    Notify me of follow-up comments?



    © Copyright 2003-2021 - Larry Hobbs - All Rights Reserved.