Empatic (120 mg Zonegran SR plus 360 mg Wellbutrin SR) caused weight loss of 12.1% in 11 months

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Tuesday, October 14, 2008 7:38 am Email this article
People given Empatic, a combination of 120 mg of sustained-release Zonegran (zonisamide) plus 360 mg of sustained-release Wellbutrin SR (bupropion), lost an average of 12.1 percent of body weight after eleven months according to a press release from Orexigen Therapeutics, the company developing the drug. Subjects

Subjects: 45 of 85 completed the study

Of the 85 people who started the study with this particular dose of the drugs, 45 completed it (53 percent).

 

10% Weight Loss

Two-thirds of patients lost at least 10%

Half of patients who completed the study (25 of 47) lost at least 10 percent of their body weight.

REFERENCE

Landbloom R. Long term weight loss from a dose optimization study with zonisamide sr and bupropion sr. Presented at: The obesity society annual scientific meeting; oct. 5, 2008; phoenix. abstract 61-OR, according to Company Press Release “Orexigen(R) Therapeutics Reviews Significant Data Regarding Its Obesity Product Candidates : Empatic™ Shows Long-Term Weight Loss, Improved Quality of Life; Contrave(R) Reduces Rate of Metabolic Syndrome by Half”:http://ir.orexigen.com/releasedetail.cfm?ReleaseID=338736

 

Articles on the same subject can be found here:

• Empatic (Zonegran plus Wellbutrin)

• Wellbutrin (bupropion)

• Zonegran (zonisamide)