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  • Empatic (360 mg Zonegran SR plus 360 mg Wellbutrin SR) caused weight loss of 14% in 11 months

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    Tuesday, October 14, 2008 7:01 am Email this article
    People given Empatic, a combination of 360 mg of sustained-release Zonegran (zonisamide) plus 360 mg of sustained-release Wellbutrin SR (bupropion), lost an average of 14 percent of body weight after eleven months according to a press release from Orexigen Therapeutics, the company developing the drug. Subjects

    Subjects: 56 of 87 completed the study

    Of the 87 people who started the study with this particular dose of the drugs, 56 completed it (64 percent).


    10% Weight Loss

    Two-thirds of patients lost at least 10%

    Two-thirds of patients who completed the study (37 of 56) lost at least 10 percent of their body weight.


    Landbloom R. Long term weight loss from a dose optimization study with zonisamide sr and bupropion sr. Presented at: The obesity society annual scientific meeting; oct. 5, 2008; phoenix. abstract 61-OR, according to Company Press Release “Orexigen(R) Therapeutics Reviews Significant Data Regarding Its Obesity Product Candidates : Empatic™ Shows Long-Term Weight Loss, Improved Quality of Life; Contrave(R) Reduces Rate of Metabolic Syndrome by Half”:http://ir.orexigen.com/releasedetail.cfm?ReleaseID=338736

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