Zonegran (zonesamide) causes average weight loss of 5% after eight months

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Tuesday, April 26, 2005 6:30 am Email this article
Zonegran (zonesamide) causes an average weight loss of 6 percent of body weight after eight months compared to 1 percent for those given a placebo according to a analysis by the RAND Corporation.

In other words, those given Zonegran (zonesamide) lost 5 percent of body weight more than those given a placebo

One study

Their analysis only included one study.

Doses: 100 mg per day increased to 600 mg maximum

The dose was started at 100 mg per day and increased, as necessary, to a maximum of 600 mg per day.

REFERENCE

Li Z, Maglione M, Tu W, Mojica W, Arterburn D, Shugarman L, Hilton L, Suttorp M, Solomon V, Shekelle P, Morton S. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med. 2005 Apr 5, 142(7):532-46.

AUTHOR’S CONTACT INFORMATION

Southern California Evidence-Based Practice Center
RAND Health Division
1776 Main Street
Santa Monica, CA 90401-3208
Tel: 310-393-0411
Fax: 310-393-4818

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