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Low testosterone in men: Metabolic syndrome increases the risk 2.6-fold
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Tuesday, November 23, 2004 12:48 pm Email this article
Metabolic syndrome increases the risk of low testosterone in men 2.6-fold according to a new study from Finland.
Low testosterone defined as less than 11 nmol per literLow testostone was defined as total testosterone levels being less than 11 nmol per liter.
Low testosterone 1.9-times more likely after adjusting for BMI and low testosterone to start
After adjusting for body mass index (BMI) and low testosterone levels at the start of the study, metabolic syndrome still increased the risk 1.9-fold.
Low free testosterone defined as 225 pmol per liter
Metabolic syndrome was also associated with low free testosterone levels, defined as less than 225 pmol per liter, although the association was weaker than with total testosterone.
Smoking reduced the risk of low testosterone
Smoking reduced the risk of men with metabolic syndrome developing low testosterone levels, however, the effect was not statistically significant.
Conclusion: Prevent abdominal obesity and metabolic syndrome in order to reduce the risk of low testosterone in men
“Prevention of abdominal obesity and the accompanying metabolic syndrome in middle age may decrease the risk of [low testosterone] in men, especially in those who quit smoking,” the authors of study concluded.
REFERENCE
Laaksonen D, Niskanen L, Punnonen K, Nyyssonen K, Tuomainen T, Valkonen V, Salonen J. The metabolic syndrome and smoking in relation to hypogonadism in middle-aged men: a prospective cohort study. J Clin Endocrinol Metab. 2004 Nov 9.
AUTHOR’S CORRESPONDENCE
D. Laaksonen
Departments of Medicine
Kuopio University Hospital
Kuopio, Finland
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